Ocular Pathology

Anatomy and pathology of the human eye. Use it to review eye pathology for Ophthalmology Board Review or OKAP.

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Thursday, December 21, 2006

What is a dentate pearl?

Dentate Pearl
Definition: degenerative lesion of the dentate process that is characterized by a nodule of calcification beneath the retina.
Incidence/Prevalence: Dentate pearls are commonly seen in autopsy eyes.
Clinical: Occasionally dentate pearls are seen clinically with scleral depression. The dentate pearl is considered a degenerative lesion and has absolutely no known clinical significance except that it should be recognized as such when observed.
Gross Pathology: Under the dissecting microscope the dentate pearl appears as a yellow, slightly opalescent, sphere (hence pearl) that is in the base of the dentate process (arrow 1). The dentate pearl is usually apparent near the base of the dentate process.

Histopathology: After sectioning the dentate pearl is a calcified sphere or nodule that is located beneath the surface retina and often beneath the retina and pigment epithelium (arrow 2).

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